Episode #144 [mp3] of The Skeptics Guide to the Universe featured an excellent interview with Simon Singh, the renowned science-writer and journalist. Singh was on the show to discuss his upcoming book, Trick or Treatment?: Alternative Medicine on Trail. Singh is well-spoken and comes across as eminently reasonable and very knowledgeable. Unsurprisingly, Singh (and his co-author, Edzard Ernst) conclude there isn't much to most alt med modalities since they are "either unproven or are demonstrably ineffective, and several alternative therapies put patients at risk of harm". The interview is well worth listening to.
(See also: The Times' review of Trick or Treatment?)